ACUTE MOUNTAIN SICKNESS

Mountain sickness is a cluster of symptoms (not a disease) consisting of some combination of headache, nausea, anorexia, fatigue, dizziness, shortness of breath and insomnia. Caused by a lack of oxygen when one ascends at too rapid a pace, it usually occurs above 8,000 feet (2,438.3 meters). The range of symptoms making up mountain sickness shares many clinical features but can be divided into three syndromes:

  • Acute mountain sickness (AMS) - usually a benign condition with symptoms as noted above. Usually relieved by a short descent or slowing down the rate of ascent.
  • High altitude cerebral edema (HACE) - usually occurs only at very high altitudes. Symptoms include headaches, confusion, hallucinations, poor judgment. This condition requires immediate treatment consisting of descent and supplemental oxygen; dexamethasone may be prescribed.
  • High altitude pulmonary edema (HAPE) - symptoms include rapid onset of breathing, nocturnal shortness of breath, chest pain, confusion, headache, cough (which may be bloody). This condition requires immediate treatment consisting of descent and supplemental oxygen.

Anyone ill at high altitudes with any of the symptoms noted above should be assumed to have some variety of mountain sickness. This implies the treatment will include standard medication protocols, descent and consideration of evacuation. It's difficult to predict whom AMS, will affect, as susceptibility varies among individuals. A previous episode does not always indicate the occurrence of future episodes. Men and women appear to be affected equally and younger people are more adversely affected than older people. Good aerobic conditioning does not seem to confer a protective effect. Of course, it's always preferable to be in good physical condition prior to strenuous trekking. Travelers with conditions such as pulmonary hypertension, sickle cell disease or symptomatic cardiovascular disease should not travel to high altitudes (i.e., over 8,000 feet; 2,438.3 meters).

If you have a particular medical problem, or potential problems, you may need special counseling and preparation. The major concern may not be the altitude, but rather the remoteness of the journey where medical care may not be available.

The rate of ascent recommended by most authorities - 984.3 feet (300 meters) a day for two days when climbing above 9,843 feet (3,000 meters), slowing down to just 492.2 feet (150 meters) per day thereafter - is too slow for enthusiastic climbers and is seldom heeded.

Other preventive recommendations for climbers include: (1) eat a high-carbohydrate diet that is low in salt and fat, (2) drink extra water because increased respiration and drier air at high altitudes causes dehydration, (3) try to sleep at a lower elevation than the height of your climb that day, (4) stay warm, dry and avoid overexertion, (5) avoid cigarettes and alcohol, (6) apply sunscreens and lip balm liberally, (7) wear sunglasses for protection against sun rays that are much stronger than at sea level, (8) take aspirin or alternative medication for altitude headaches (9) talk to your health care provider about the use of Diamox® as a preventive medication.

Treatment consists of: (1) early recognition, (2) descent (the only safe management), (3) supplemental oxygen, (4) lightweight, pressurized, portable, inflatable bag (such as the Gamow bag from DuPont) and (5) medications (See below).

Options for medications include:

  • Diamox® (acetazolamide) 125 mg., 250 mg and 500 mg sequels. This is the first drug of choice for prevention of mountain sickness.
  • Decadron® (dexamethasone) 4 mg. Use only for treatment, not prevention, except in unusual situations.
  • Nifedipine 20 mg. Use every six hours for pulmonary edema when descent is not possible. Should not be used routinely.

Based on CDC, Health Information for International Travel 2000-2001, DHHS, Atlanta, GA, 2001; and Dr. Richard Thompson's book Well on the Road - A Practical Guide for the International Traveler, 2002.